Les 3 molécules de l’année (1/3)

Telithromycine is the first ketolide on the market. Its characteristics are the two sites fixation on the bacterial ribosomia and as a consequence a good activity on the majority of penicillin and macrolides resistant bacteria, included S. pneumonia and S. pyogenes. Telithromycine represents an alternative to b-lactames and moxifloxacine to treat communautary pneumonia, bacterial pharyngo-amygdalitis, suppurative sinusitis and bronchitis. There are nevertheless problems with drugs interactions and risk of resistance development.